Abstract
We measured handgrip exercise-mediated responses of active palmar sweating in 24 right-handed healthy subjects (4males, 20 females; 20.5±1.3 yr. old), volunteered with written informed consent, by using newly developed ratemeters (SKD-2000, Skinos Co. Ltd., Nagoya, Japan). Fourteen subjects performed the 5-second isometric right-handgrip exercise (IHG) at 100, 75, 50 and 25% of maximal voluntary contractions (MVC) in this decreasing order at 3-minute interval in seated and supine positions. Ten subjects also performed the 5-s right-IHG in the same procedure in seated position without pressure, and with pressure on the back. The loss of water (mg/cm2/min) was calculated separately between pre-operational responses during verbal explanation of the task (1 min) and IHG-mediated operational responses during/after the execution of the 5-s IHG task (1 min). The 5-s IHG caused a significant increase of ipsi-and-contra lateral active palmar sweating, dependent upon the IHG intensity (100-25% MVC), and resulted in no habituation. The pre-operational responses and IHG-mediated operational responses were significantly reduced by changing posture form the seated to the supine or to the seated with pressure on the skin of the back. [Jpn J Physiol 55 Suppl:S190 (2005)]