Abstract
Multiple-site optical recording methods, using voltage-sensitive dyes and a multi-element (16 X 16) photodiode array, were employed to simultaneously monitor action potentials from many sites in the isolated rat atrium preparation. The wavelength of the incident light was changed within the range of 500–750 nm, and the action spectra were measured for several voltage-sensitive dyes. These dyes belonged to merocyanine-oxazolone, merocyanine-rhodanine and oxonol groups. Most of the dyes had the action spectra which were similar to those reported in the previous report. However, some dyes exhibited different spectra from those of other preparations. Species-to-species difference of the action spectrum of the voltage-sensitive dye would be discussed. [Jpn J Physiol 55 Suppl:S86 (2005)]
