Abstract
We participate in the project to establish the technique to diagnose a nerve disease by the injury of the shake of infancy at the early stage. The purposes of our research is acquiring the method of detecting the injury to the brain by the diffusion weighted image with the Fractional anisotropy (FA) image and the Trace index (TI) In this presentation, we show the initial data with adult mouse acquired in establishment and the image of the infant rat.In the FA image of the mouse brain, a high numerical value was shown in corpus callosum (0.65±0. 03), and about twice the numerical value was shown to each region of the cerebral cortex (e.g. M1:0. 34±0. 01 and S1Tr:0. 32±0. 01). Moreover, the difference between the regions was not remarkable in the cerebral cortex. However, numerical value at the dentate gyrus (0.25±0. 01) was significantly low compared with molecular cell layer and pyramidal cell layer (Mol:0. 38±0. 05,Py:0. 28±0. 03). In the TI image, the numerical value of the corpus callosum was the same to the cerebral cortex area. Dentate gyrus (0.87±0. 01 10−3mm2/sec) showed that numerical values were lower than others (Mol: 1.07±0. 02,Py1.03±0. 02) in the hippocampus. On the other hand, infant age rat's FA image almost showed the description pattern similar to images of mouse. The numerical value of FA indicated a constant value at any stage of development in the corpus callosum, and a significant difference by the day age could not be confirmed. [J Physiol Sci. 2007;57 Suppl:S144]
