Evaluation of Refractory Liver Diseases by Mahalanobis-Taguchi System 

－Diagnosis of Autoimmune Liver Disease using Mahalanobis-Taguchi Adjoint Method－

Abstract

Among the various types of liver disease, autoimmune liver disease is often difficult to diagnose, and as a refractory disease, it is also difficult to treat. The reasons are the many types of overlapping data produced from liver histological findings, blood test results, and the like. Even the results of a liver biopsy sometimes fail to yield a diagnosis. The authors therefore used the Mahalallobis-Taguchi adjoint (MTA) method, which is one technique in the Mahalanobis-Taguchi (MT) system, to diagnose and distinguish autoimmune liver disease. This enabled several types of pathological conditions to be evaluated quantitatively, as reported herein.