Abstract
Biotechnology makes use of recombinant bacteria for synthesis and production of organic compounds like proteins and enzymes. A bacteria (E.coli) is transformed with a plasmid containing a gene and an expression promoter for production of the desired protein. The batch process starts with an appropriate cell growth followed by induction and activation of the expression promoter. Fermentation pararneters affecting the production performance are investigated. Dynamic analysis reveals adaptation of fermentation conditions for optimum production rate. Thus parameter settings have been predicted that lead to a doubling of the protein production.
