2011 Volume 60 Issue 10 Pages 433-442
Recently radiotherapy is making a great advancement in the field of cancer treatment in Japan. Physical and technological achievement by concentrating radiation to tumor tissues has been a major reason for the advancement. On the other hand, biological approach has also been thought to be important. Especially, recent progress on molecular biology is providing an innovative changes in the field of radiobilogy. Many phenomenological findings accumulated in this field are going to be resolved from a view of molecular mechanisms. I will review a recent trend of radiobiology in addition to historically important events discovered in the classic radiobiology.