A CASE OF ADENOCARCINOMA OF THE ESOPHAGUS DEVELOPING AT THE SITE OF CORROSIVE STRICTURE

Abstract

A 53-year-old woman with a 28-year history of dysphagia was admitted to the National Tosei Hospital because of the increasing intensity of her complaint. The patient suffered from corrosive esophagitis and subsequent stricture caused by ingestion of sulfuric acid 28 years earlier. An upper gastrointestinal series revealed circular stenosis with an irregular elevated lesion at the site of the lower esophagus. Carcinoma developing at the site of the corrosive esophageal stricture was suspected and resection of the lower esophagus followed by intrathoracic esophagogastrostomy was performed. Histopathological studies of the resected specimen showed papillary adenocarcinoma at the site of the stricture of the lower esophagus lined by columnar epthelium.
The papillary adenocarcinoma of this patient was believed to have developed at the lower esophagus which had been transformed into Barrett's esophagus through chronic esophageal irritation following corrosive esophagitis and continuing dysfunction of the EC junction.
This case is believed to be the first report of esophageal adenocarcinoma developing at the site of corrosive stricture found in either Japanese or foreign literature.