Abstract
Three cases of gastric carcinoid experienced in our department of surgery during the last 8 years are reported. The incidence among cases of gastric cancer during the same period was 0.8%. Case 1 showed almost the same finding as that seen in early gastric cancer IIa+IIc in the body of the stomach, with pernicious anemia. Only one case of association with pernicious anemia, as seen in this case, has been reported in the Japanese literature. Case 2 had MEN-1-type adenomatosis. In this case carcinoid was found as a submucosal-type tumor in the body of the stomach. This case was multihormonal. In case 3, extremely pronounced gastric secretion suggested Zollinger-Ellison syndrome, but because of emergency surgery, serum gastrin lvels were not measured. Polypoid-type carcinoid on the pyloric ring and gastric ulcer in the angle were found. Cases 1 and 2 had hypergastrinemia and in case 3 hypergastrinemia was suspected clinically. All of these cases failed to demonstrate gastrin in the tumor by the peroxidase-anti-peroxidase method. Glucagon in the tumor was present in all three cases. In case 2, hyperinsulinemia and positive staining for insulin in the tumor were also revealed.
