The journal of the Japanese Practical Surgeon Society
Online ISSN : 2189-2075
Print ISSN : 0386-9776
ISSN-L : 0386-9776
GRAVES' DISEASE ASSOCIATED THYROID CANCER
A CLINICAL STUDY OF 6 CASES AND LITERATURE REVIEW
Nobuji YOKOYAMAJunichi YOSHIZAWAHisashi USUKIRyuji HIRAIHiroyuki SOGAShoukichi KOMATSUBARAShigeru TERAMOTOToshiki MISUMI
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JOURNAL FREE ACCESS

1987 Volume 48 Issue 6 Pages 805-810

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Abstract
The relationship of thyroid carcinoma to Graves' disease is unclear. We report our experience with Graves' disease and concurrent carcinoma and review the literature. During the 20-year period from January 1966 through December 1985, 127 patients were treated at our department for Graves' disease. Thyroid carcinoma complicated 6 cases (4.7%) classified as latent (3 cases), occult (2 cases) and clinically significant (1 cases) types.
The clinicopathological study revealed that most of the nodules were less than 2cm in diameter and tended to metastasize to the regional lymphnodes and then relapse. This leads to the speculation that hyperthyroidism dose not inhibit the growth and possibly not the genesis of thyroid carcinoma. So we must take care of concurrent carcinoma in treating Graves' disease.
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© Japan Surgical Association
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