1988 Volume 49 Issue 12 Pages 2275-2281
During the past 10 years the authors experienced 117 patients with perforated gastroduodenal ulcers. There were 14 with gastric ulcers, 102 with duodenal ulcers and one with an anastomotic ulcer. They accounted for 26.4% of 442 patietns with gastroduodenal ulcer treated by surgery. The free-air-positive rate was 80.4%.
About half of the patients with perforation had a previous history of an ulcer. A study of their treatment history revealed that more than half of them had discontinued treatment of the disease, suggesting the importance of maintenance therapy for ulcers.
The mortality rate was 5.1%. A poor outcome was found in aged patients, those who had a time lapse of more than 24 hours from manifestation of symptoms to surgery, those with preopeartive complications and those with a perforated posterior wall ulcer.