Abstract
Two cases of the gigantic retroperitoneal liposarcomas resected with the adjacent organs are reported. Case 1 (56-year-old woman): A gigantic tumor (60×52×34 cm, 10.2 kg) was extirpated with left adrenal gland and the psoas muscle. Case 2 (72-year-old man): A tumor occupying the left hypochondrium (28×21×18 cm, 5.2 kg) was extirpated with the stomach and the spleen. In both cases, the histological feature revealed well-defferentiated type-dominant liposarcoma. By applying the adjuvant postoperative chemotherpy and irradiation, no recurrence has been found by the present time, for postoperative 17 months in case 1 and for 9 months in case 2.
Based on our experience and a reivew of the literatures from 1968 to 1987 in Japan, 130 cases in the Japanese adults were analyzed in terms of their clinical features and surgical treatments. Surgical resection was performed in 114 cases (87.7%) and adjacent organ resection was required in 44 cases including the kidney (24 cases), colon (10 cases), spleen (8 cases) and others.
Since the recurrence rate is still high (34.1%), aggressive and radical surgical extirpation followd by adjuvant postoperative irradiation and chemotherapy should be achieved.
