Abstract
In this paper, two cases of so-called simple ulcer of the colon locally recurred after resection for primary ulcer are presented.
The first case, a 47-year-old man, had undergone ileocecal resection due to ulcer 10 years previously. 4 years after the resection, recurrent ulcer was found at the site of ileo-ascending anastomosis, then the second resection was performed. However, clinical symptoms such as right lower abdominal pain, recurred 3 years after the second resection, and ulcer was detected again at the site of anastomosis.
The second case, a 55-year-old woman, had undergone right hemicolectomy for caecal ulcer 8 years ago. 6 years after this operation, recurrent ulcer was found at the site of ileo-ascending anastomosis.
All ulcers in the resected specimens from both cases are sharp-bordered and histologic sections showed a nonspecific inflammatory reaction, i.e., so-called simple ulce, with no signs of malignancy.
In the cases of recurrent simple ulcer, differential diagnosis from "Entero-Behcet's disease" is usually difficult just only in histological study, then intensive follow-up study should be necessary to clear such problem.