A CASE OF MALIGNANT LYMPHOMA LOCALIZED IN THE LIVER AND SPLEEN

Abstract

A 48-year-old man was admitted with the chief complaint of swelling sensation ranging from the right abdominal to the dorsal regions. Various imaging diagnoses revealed malignant lymphoma localized in the liver and spleen or metastatic tumors with unknown primary lesion. For a definitive diagnosis, splenectomy was performed. Pathological examination led to a diagnosis of malignant lymphoma, for which postoperative chemotherapy was started, but the patient died of hepatorenal insufficiency. Post-mortem examination disclosed that the lesion was localized at only the liver and spleen, which suggested malignant lymphoma was originated from either organ. Primary hepatic or splenic malignant lymphoma is so rare that only 20 or 101 cases have been reported in Japan up to 1988. Additionally, we made the literary consideration including those cases.