Abstract
Primary cancer arised in the duodenum is rare, especially an adenosquamous cell carcinoma extremely rare.
In a 45-year-old male complaining of epigastralgia, hypotonic duodenography revealed a definite stricture in the 2nd portion of the duodenum. Endoscopic biopsy showed a well differentiated adenoarcinoma. Therefore, standard pancreaticoduodenectomy was performed. Metastasis was found in the para pancreatic lymphnode. The postoperative histological examination revealed that the lesion was not related with the Vater's papilla and there was aberrant pancreas at the adjacent area. These findings suggest that the lesion might arise in the aberrant pancreas rather than in the duodenal mucosa. The patient has been well without any evidence of recurrence for 5years since the surgery.