1990 Volume 51 Issue 7 Pages 1418-1425
Among 327 patients operated on for colorectal carcinoma in Hiratsuka City Hospital during 1970-1989, 61 patients of 75 years and upward (H group) were selected and compared for the clinicopathologic details and prognosis with 57 patients under 50 years (LM group). There were no significant difference between these two groups in the rates of resection, curative resection and operative death. A significantly higher frequency of rightsided tumors was noted in H group. No significant difference was observed in the frequency of patients having distant metastases. Proportion of patients with negative regional lymph node metastasis in H group was 68.4%, whereas 47.4% in the LM group with a significant difference (p<0.05). Proportion of each clinicopathological stages due to Astler-Coller showed a significant difference between these two groups. The proportion of patients who were in stage A was 18.0% in H group, whereas 1.8% in LM group, with a significant difference (p<0.05).
Proportion of mucinous adenocarcinoma in H or LM group was 1.6% or 12.3% respectively, with a significant difference (p<0.05). Cumulative 7-year survival rates were 22.3% in H and 60.2% in LM group, with a significant difference (p<0.01). On the other hand, colorectal cancer-related 7-year survival rates in the H and LM groups were 68.5% and 81.6% respectively, of which difference was not significant. It is concluded that there is obvious Clinicopathologic difference between elderly and relatively younger patients, and that the operative indication for colorectal cancer in the elderly is justifiable and should not be restricted only by a risk factor of age.
