Abstract
In Kobe Rosai Hospital, 720 cases of resected gastric cancer managed in a past 15-year period. Multiple primary cancer in the stomach and other organs was encountered in forty-four patients, amounting to 6.1%. Twenty-eitht patients were men, and sixteen were women.
The average age of multiple primary cancers was higher than that of single stomach cancers and women patients of multiple primary cancers were comparatively younger than men.
Seventeen synchronous cancers -cancers of another organs appeared within a year- came to 38.6% and 27 metachronous cancers -cancers of another organs appeared after over a year- was 61.4%. It was also found that the average interval between stomach cancers and those of another organs was longer in women.
Among multiple primary cancers with stomach cancers, the colon cancers ranked first in men: 11 patients, 39.0% and breast cancers came first in women, 43.8%. On the whole, colon cancers ranked first, 14 cases, 31.8%, fallowed by breast cancers and rectum cancers.
When compared with single gastric cancers, a 5-year survival rate of the multiple primary cancers was lower: this was 25.0% and that was 40.8%.
Death occurred in 34 patients. The causes were due to cancers of other organs rather than single stomach cancers. Direct causes of death were chiefly by peritonitis carcinomatosa and metastasis of major organs. Fourteen deaths by another diseases were also reported.