CLINICAL AND PATHOLOGICAL ANALYSIS OF MUCINOUS CARCINOMA OF THE COLON AND RECTUM

Abstract

Sixteen patients diagnosed as mucinous adenocarcinoma out of 511 patients with colorectal cancer were clinicopathologically studied. the male-to-female ratio was virtually 4:12, there being a female dominance. Thirteen patients were older than 60 years of age. Each half of the tumors were located in the right and left colon respectively. Nine patients showed Borrmann 2 in the gross type. Peritoneal dissemination was observed in 2 patients, but no liver metastasis. Incidence of lymph node metastasis or wall invasion deeper than pm was 71.4% or 92.8%, respectively. All patients underwent tumor resections and 11 (78.6%) patients underwent curative resection. Six patients died of recurrence in intraperitoneal region within 2 years after operation. The 5-year survival rate in all patients was as relatively low as 50%, except 3 deaths due to other diseases and one of unknown prognosis.
In conclusion mucinous carcinomas of the colon and rectum were predominantly in an advanced stage and commonly developed periotoneal recurrence including local recurrence. Thus, the prevention of local and peritoneal recurrence is a key point in the treatment of mucinous adenocarcinomas of the colon and rectum.