Abstract
This paper reports on patient with Gardner's syndrome. A 51-year-old man was admitted to the hospital because of diarrhea and bloody stool. Barium enema and colonofiberscopy disclosed multiple polyps and two advanced cancers of the transverse colon and rectum. Gastrofiberscopy revealed fundic gland polyposis. Soft tissue tumor of the left shoulder was excised and diagnosed as lipoma histologically. Osteomas in the mandibula and the sacrum were also discovered. A family history of polyposis coli was denied. A proctocolectomy and J ileal pouch anal anastomosis were performed by the invagination method using PCEEA. The resected intestine showed approximitry 2500 polyps, diffusely scattered over the intestinal mucosa from the cecum to the rectum. Histologically, the polyps showed the findings of tubular, tubulovillous and villous adenoma, and the cancers of the transverse colon and the rectum were reported to show the well differentiated adenocarcinomas, infiltrated to subserosa and proper muscle layer, respectively. The loop ileostomy was closed in 8 months after surgery. Postoperative defecation was good.