Abstract
Three cases of malignant fibrous histiocytoma (MFH) arising in the abdomen and retroperitoneum are described. Case 1 was a 34-year-old man. There was a history of receiving radiotherapy after ascensus resection of the scrotum, and in the course of close medical observation, a tumor appeared in the peritoneum. Operation was performed and the tumor was found to be a MFH. The patient experienced a local recurrence which well responded to chemotherapy, however, he died of lung metastasis. Case 2 was a 79-year-old man. He had a MFH in the mesentery of ileocecal region which rolled up the ileum, where a part of the ileum necrosed. Excision of the ileum and ascending colon was performed. Case 3 was a 72-year-old woman, who was referred to the hospital because of an abdominal tumor. Operation was carried out and a huge MFH in the retroperitoneum invading the diaphragm and right kidney was found.
Generally, MFH has poor prognosis and is liable to recur locally and to metastasize, in that sufficient resection of the tumor involving the surrounding connective tissue is essential. Adjuvant chemotherapy, however, can produce an excellent clinical effect in some cases and should be applied as possible as we can.
