The journal of the Japanese Practical Surgeon Society
Online ISSN : 2189-2075
Print ISSN : 0386-9776
ISSN-L : 0386-9776
STUDY OF POSTOPERATIVE ENTERITIS CAUSED BY METHICILLIN CEPHEM-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA)
COMPARISON BETWEEN SEVERE GROUP AND MILD GROUP
Yoshiharu NISHIMURAHiroaki TAKENAKAKazuhiro IWASEAkihiko YAGURAKatsuhide YOSHIDOMETakahito OONISHIMotohide TAKAGAKITohru ISHIZAKAToshiya BESSHOToshihiro OOHATAMasayoshi INOUESenya OOSHIMATomoyuki TANAKAAtsuo KATAI
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1992 Volume 53 Issue 11 Pages 2569-2573

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Abstract
In this study some factors affecting the severity of postoperative MRSA enteritis and auxiliary diagnostic values for predicting the severity were examined. Twelve patients were subjected to the study and were allocated to severe (6 patients) and mild (6) groups. Patients allocated to severe group had renal dysfunction or a high fever over 39°C, or required additional volume load of more than 2000 ml daily. There was no significant difference between the two groups in the preoperative and intraoperative factors. The postoperative period to the onset of enteritis was significantly (p<0.05) shorter in the severe group than in the mild group, [3.7±1.1 (Mean±SD) days v.s. 7.1±2.7 days]. There was no significant difference in leukocyte count at the onset of enteritis, though a leukocyte left shift was significantly greater in the severe group than in the other (72±26%, v.s. 6±4%). The maximum dilution factor of Toxic Shock Syndrome Toxin-1 (TSST-1) was significantly higher in the sever group than in the other (27.4±0.4 v.s. 26.6±0.5). The following factors may suggest the severity of MRSA enteritis: The postoperative period to the onset of the enteritis is less than 4 days; a leukocyte left shift at the onset of enteritis is great; and the maximum dilution factor of TSST-1 is high.
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