1992 Volume 53 Issue 2 Pages 309-312
Of 294 cases of colorectal cancer treated at Asahikawa Kosei Hospital from Jan. 1985 to Aug. 1990, 9 cases of poorly differenciated carcinoma (PDC) and 10 cases of mucinous carcinoma (MC) were clinicopathologically compared with the remaining 275 cases of differenciated carcinoma (DC). Average age was low and the tumor was more frequently found at right side of the large intestine in the former two groups. Microscopical wall invasion was deeper than or equal to subserosa (ss) in all 19 cases.
Clinicopathological features of PDC were high incidences of lymphnode metastasis (89%), lymphatic invasion (77%), venous invasion (56%) and liver metastasis (33%), all of which were higher than those of DCs. In contrast, it was characteristic that MC had a low incidence of liver metastasis (0%) and high incidence of peritoneal dissemination (40%), indicating a possible different mechanism of metastasis. Prognosis of the patients with PDC was the worst and 4 years survival was 33%. In treatment of PDC, we should remember that it tends to invade the surrounding organs and can metastasize distantly in a high incidence.
