Abstract
A relatively rare operated case of signoid colon cancer synchronously associated with multiple myeloma (MM) is reported.
A 64-year-old man pointed out hypergammaglobulinemia from the biochemical examination was diagnosed as having IgG (λ) type MM by electrophoresis and bone marrow biopsy. Two weeks after the melphalan treatment was begun, he underwent a barium enema and was diagnosed as having a sigmoid colon cancer. sigmoidectomy with lymph nodes dissection was performed. The patient left our hospital 30 days after the operation. Unfortunately he acquired a pulmonary infection due to pancytopenia caused by MM and died 11 months after the melphalan treatment, or 9 months after the operation.
We should use caution with any other cancer patient which is complicated by MM. It is rare that colorectal cancer is associated with MM, but not rare that MM is associated with malignant disease. We should pay attention to renal failure and leakage from colorectal anastomosis in the operative management of colorectal cancer complicated by MM, because MM is a high risk disease accompanying with renal dysfunction and hypoalbuminemia.
