Abstract
The occurrence of corrosive stenosis of the esophagus is reportedly 0-16.4%, which were mostly reported in Europe and the USA and rarely in Japan. Here, a case of esophageal cancer occurred 50 years after swallowing a drug by mistake is described. A 69-year-old man was admitted to the hospital because of difficulty in swallowing. When the patient was 19 years old, he swallowed an alkaline agent by mistake and developed a corrosive stenosis of the esophagus. Since July, 1989, about 50 years later, dysphagia was enhanced and esophageal endoscopy revealed a cancer lesion in the scar in the lu region. On October 5, subtotal esophagectomy with lymph node dissection of three regions was performed under a diagnosis of esophageal cancer associating with corrosive stenosis of the esophagus. In the excised esophagus a wide-ranging scar was confirmed in the upper to middle part of the thoracic esophagus, and a moderately differentiated squamous cell carcinoma of type 3, 4.0×4.5 cm in size, was found in the scar tissues in the lu region. The carcinoma infiltrated into the adventitia, and was a2, ly(+), and v(+), however, no lymph node metastasis was noted, it being (n0) in stage III. Postoperative course was uneventful and the patient recovers his daily and social activities.