Abstract
In 569 resected cases of cancer of the colon and rectum, mucinous carcinoma occurred in 24 cases (4.2%). Twenty-one of the 24 cases, of which clinicopathological features were known in detail, were clinicopathologically compared with 355 cases of well differentiated adenocarcinoma, the most common type.
Mucinous carcinomas were commonly found in the colon, especially in the right side, with a significant difference (p<0.01). Most cases were in an advanced stage. Carcinomas with the invasion depth of s (a2) and si (ai) were more frequently seen (p<0.01). The positive rate of lymph node metastasis of 47.6% in mucinous carcinomas was higher than that in well differentiated adenocarcinomas, and the lymphatic vessel invasion rate of 100% was significantly higher than the other (p<0.05). Five-year survival rate was 54.6% in all 21 cases, or 63% in curative resection cases, either of which was lower than those in differentiated adenocarcinoma cases, though there was no significant difference.
In view of the above features, extensive lymph node dissection and complete excision of tissues surrounding the lesion would be necessary in the surgical treatment.
