Abstract
A 36-year-old man was admitted to the hospital because of furunculoid papule in the right thigh. There was a 10-year history of ulcerative colitis, for which the patient had been sometimes taking salazopirin. He was seen at the department, because furunculoid papule which appeared about 2 weeks before showed a rapid enlargement even though antibiotic regimen. At that time the papule had become a circle-like ulcer with a diameter of 8 cm and presented with characteristic findings of pyoderma gangrenosum. General findings included a low-degree fever, tachycardia, and diarrhea. Stolls were positive for occult blood. Barium enema and rectoscopic examination revealed ulcerative colitis findings. Accordingly the patient was diagnosed as phoderma gangrenosum associated with ulcerative colitis in an active phase. Salazopirin regimen was immediately started. As a result, rapid remission in the papule could be attained, and simultaneously, general findings resulting from ulcerative colitis disappeared.
