Abstract
In order to determine prognostic factors of Borrmann type 4 gastric carcinoma, 8 long-term survivors and 23 short-term recurrent patients with stage III gastric cancer, who were operated on at the department in a recent 14-year period, were compared for location and size of the tumor, histologic type, serosal invasion, lymph node metastasis, vascular invasion, and mode of recurrence. In evaluation of patients in stage III, which was free from peritoneal and hepatic factors, it was clarified that serosal factor was more valuable than lymph node factor. Lymph node invasion and tumor diameter were also important prognostic factors. Peritoneal lavage cytology revealed carcinoma cells in all patients who had serosal invasion without macroscopic peritoneal dissemination. Analysing the types of the recurrence, the most common type was peritoneal dissemination, that is, prevention of peritoneal dissemination was essential in postoperative adjuvant therapy in patients with Borrmann type 4 gastric cancer.