Abstract
A neurogenic sarcoma of the stomach is very rare.
A 70-year-old woman was admitted to the hospital for examination, because she was pointed out to have a mucosal abnormality of the cardia at mass screening survey of the stomach. Abdominal X-ray and endoscopic studies revealed an elevated lesion on the greater curvature of the Cardia. Further examination disclosed that the tumor was located from the left diaphragm to left renal hilus, and compressed the left lobe of the liver and spleen. Owing to hemorrhage and necrosis, its content was heterogenous, therefore drainage was done. Biopsy specimens offered a suspicion of leiomyosarcoma. The tumor did not respond to chemotherapy. Total gastrectomy was performed. The tumor was 24.0×18.0×18.0cm in size with invasion adjoining the spleen. The cut surface showed relatively hard, white and homogenous with little necrosis. Microscopic appearance revealed spindle shaped cells with a pattern of streaming in the same direction. Histological examinations, including negative actin staining and positive S-100 protein staining, led to the diagnosis of neurogenic sarcoma of the stomach.
