Abstract
This paper presents an unusual difficulty encountered in clinical differentiation between reactive lymphoreticular hyperplasia (RLH) of the stomach and malignant lymphoma (ML) of the stomach (diffuse lymphoma, mixed type). A 62-year-old female had epigastrial discomfort. Gastorofiberscopy and rentogenography revealed coarse granuliform degenerations with irregular ulcer over the area extending from great curvature of angle, lower and middle portion of the stomach to the posterior wall. Notwithstanding the diagnosis of RLH resulted from biopsy she had to undergo a surgical operation due to still undeniable sign of ML. Pathological findings, however, entailed ML localizing in 3 spots within a wide ranged RLH impairment. Immunohistochemically, RLH impairment was stained by polyclonal antibody, while ML impairment by monoclonal antibody. Of obvious note in this clinical case is the coexistence of wide ranged RLH and partially ranged ML, wherein a transition from the former to the latter is highly probable.
