1994 Volume 55 Issue 11 Pages 2903-2907
Splenic peliosis is a rare disease. We experienced a patient with the disease who died of intraperitonealhemorrhage and disseminated intravascular coagulation (DIC) resulting from splenic rupture.
A 55-year-old man developed abdominal pain and hypotension when he was staying at a nearby hospital complaining of vomiting and back pain. The patient was transferred to the hospital under a diagnosis of intraperitoneal hemorrhage. On admission no bleeding spots on the skin were noted. RBC was 2810000/mm3, WBC was 17800/mm3, and Plt was 14000/mm3. There was no history of any underlying disorders or of medication with steroids.
Ultrasonography and computed tomography revealed multiple splenic hematoma with intraperitoneal hemorrhage. Transarterial embolization (TAE) of splenic artery and splenectomy were performed. Remission in general condition could not be attained and the patient died.
The excised tumorous lesions of the spleen were bloodfilled cavities surrounded with splenic parenchyma. Pathological diagnosis was splenic peliosis. Autopsy disclosed the same lesions within the bone marrow. The development of DIC due to hemorrage of multiple intrasplenic and bone marrow cavities was responsible for massive bleeding and death.
