Abstract
Osteomyelitis due to candida infection is very rare. This paper presents two cases of candida osteomyelitis following esophagectomy, together with a review of the literature.
Case 1: A 65-year-old male developed wound infection of the thoracotomy wound, 27 days after esohagogas-trectomy, distal pancreatectomy and splenectomy for an esophageal cancer. Despite several debridement procedures over a six month period, the wound was not improved. Surgical cultures revealed Candida albicans. The patient underwent a partial resection of 5-8th cartilage and extirpation of abscess cavity with combinations of antimycotic therapy, which resulted in complete wound healing.
Case 2: A 46-year-old male failed candida osteomyelitis on the left side of the anterior chest wall three months after esophagectomy for an esophageal cancer. He could recover and the wound was improved to cure after-months administration of antimycotic agent and several debridements of the wound.
The total parenteral nutrition (TPN) and broad-spectrum antibiotics were given for postoperative care in both patients. These two cases of candida osteomyeritis might be caused by TPN and/or widespread use of antibiotics.
