Preoperative therapy is most commonly employed to improve both the resectability and curability in locally advanced breast cancer. Though there is a recent increasing tendency of performing breastsparing operation with an increase in detection of early breast cancer, preoperative therapy it has been rarely applied for down staging, to early breast cancer (Stage I, II). Here, the authors present a case of Stage II breast cancer that was sucessfully treat with conservative surgery after achieving complete remission by a 4 month oral chemo-endocrine therapy (5'-deoxyfluorouridine: 600 mg/day, and Tamoxifen: 20 mg/day), not with standing the carcinoma of the breast was indicated mastectomy prior to the conservative surgery. The role of preoperative therapy for early breast cancer is still unclear, but it may become another treatment option in the future.