1994 Volume 55 Issue 9 Pages 2331-2336
A case of leiomyosarcoma of the stomach in a 79-year-old man in presented here. The patient underwent subtotal gastrectomy for a gastric leiomyosarcoma at another hospital in 1985. At the same hospital be underwent excisions two times for metastases to the mesentery, liver (S3 and S8), and abdominal wall in 1987. Thereafter the patient underwent excisions at the hospital for metastasee to the sigmoid colon in 1990; measenterium in 1991; liver (S8) and chest wall in 1992; liver (S8) in May and the same organ (S2 and S3), mesenterium, and retroperitoneum in July 1993. The patient is alive for 8 years after 7 times operations for metastatic foci following the first operation. When the primary and metastasized lesions were compared for the numbers of karyokinesis and Ag-NORs, the both numbers were higher in the metastatic lesions than those in the primary lesion. These findings indicated that the proliferation activity of the metastatic cells was accerelated.
