Abstract
We experienced a patient suffering from frequent anal bleeding whose bleeding site was difficult to be determined even by upper and lower endoscopic examinations. To identify the lesion of bleeding, an exploratory laparotomy was performed. It was found that the cause of bleeding was due to multiple peptic ulcers of the small intestine. Myeloblasts appeared in the peripheral blood with the time. Bone marrow biopsy showed the typical myelofibrosis. It is known that myeloproliferative diseases including Polycythemia vera are often accompanied with peptic ulcer. In this case; however polycythemia was not evident because of anemia due to frequent anal bleeding for intestinal multiple peptic ulcers. This report describes the case of myeloproliferative disease that presented difficulty in diagnosis and was eventually found by multiple peptic ulcers.
