Abstract
Nosocomial propagation of multidrug-resistant Staphylococcus aureus was investigated in patients who underwent gastroenterologic operations. A cluster analysis was attempted to clarify the association of factors among 32 patients, 204 bacterial isolates, and drugs administered. The results showed that first-and second-generation cephalosporins, penicillins, and aminoglycosides were associated with increased resistance. Drugs of each group were given for an average of 5-9 days until the detection of the bacteria.
The results suggest that the use of first-and second-generation cephalosporins and penicillins during gastroenterologic operations was related with increased resistance and thus encourage to minimize their prophylactic administration.
