Abstract
The purpose of our study was to evaluate the clinicopathological features and treatment of patients with ovarian metastases derived from a colorectal cancer. The clinical records of 172 patients who underwent resection of primary colorectal cancer at our department from 1980 to 1993 were reviewed. Eleven of them (average age: 52.9 y.o) had ovarian metastases from colorectal cancer. Eight patients had synchronous metastases and three had metachronous metastases. The primary tumor was in the rectum in four cases; in the sigmoid colon in three; in the ascending colon in one and in the cecum in three. Synchronous metastases disseminated in the peritoneal cavity were found in all patients and two of them also developed peritoneal metastases afterwards. Following resection of the primary tumor, four patients were treated with continuous hyperthermic peritoneal perfusion (CHPP), and two of them, who underwent an additional oophorectomy and hysterectomy, were still alive with no evidence of recurrence at the time of this review. These findings indicate that combination therapy of oophorectomy, hysterectomy and CHPP is effective as treatment for ovarian metastases derived from colorectal cancer.
