Abstract
A 30-year-old woman was admitted to our hospital because of sudden hematemesis. Emergency endoscopic examination of the stomach revealed a submucosal tumor with giant ulcer and another submucosal tumor. The former was located in the upper corpus, and the later was in the lower corpus.
Biopsies from the ulcer edge showed only leiomyoma. However, the size (about 5cm in diameter), appearance, easy bleeding, and diagnostic images suggested leiomyosarcoma. Accordingly, operation (total gastrectomy+D2 lymph node resection) was performed. Histopathological examination revealed that two lesions were other leiomyosarcomas and that there was lymph node metastasis. Multiple gastric leiomyosarcomas are reported in only 10 cases (including ours) in Japan. This case is thus considered to be rare.
