Abstract
We experienced two cases of non-functioning endocrine cell tumor of he pancreas which is relatively rare. Case 1 involved a 38-year-old man. He was seen at the hospital because of back pain and was found out a huge hypervascular tumor positioned in the pancreatic tail. Infiltration into the stomach, spleen, retroperationeum, and left kidney and metastasis to the right kidney were confirmed. Biopsy under laparotomy was made. He is doing well while carring the cancer, as of 1.5 years after the operation. Case 2 involved a 34-year-old women. She was seen at the hospital because of a pancreatic tumor which was pointed out at medical checkup in other hospital. Close examination disclosed a hypervascular tumor about 3cm in diameter at the uncus of the pancreas. Pancreatoduodenectomy was carried out and the difinite diagnosis of non-functioning endocrine cell tumor of the pancreas was made.
Furthermore, a histopathological study was conducted on these two cases and autopsy cases of carcinoid glucagonoma which were accidentally found out. As a result, a significant increase in cell number per unit square in case I and an evident increase in nuclei in case 2 were ovserved.
