Abstract
In recent years, transarterial chemoembolization therapy (TACE) has been actively carried out for inoperable metastatic hepatic cancer, and the number of case reports where the treatment was effective is also increasing. In this study we report on a case of multiple hepatic metastases, which multiplied rapidly after surgery for a breast cancer, where single TACE was markedly effective, as demonstrated by the complete disappearance of the metastatic lesions on imaging.
A 47-year-old woman underwent an operation for a breast cancer at another hospital on February 4, 1993. The patient changed the hospital upon local recurrence of the cancer despite postoperative chemotherapy, where hepatic metastases were found. The hepatic metastatic foci did not respond to chemotherapy and immunotherapy and started to enlarge rapidly. The patient was admitted to the hospital. The hepatic metastases were treated with TACE (including 10mg of MMC, 10mg of ADM, 30mg of CDDP, and 20ml of lipiodol) on October 20. Since a rapid shrinking of the metastatic foci was noted, resection of locally recurring foci and bilateral ovariectomy were performed, followed by systemic chemotherapy. CT conducted 3 months after TACE confirmed the complete disappearance of the metastatic foci, and the condition could be maintained for at least 6 months. We think that aggressive TACE is also effective for hepatic metastases of breast cancer.
