A CASE OF EOSINOPHILIC GASTRITIS FORMING A HUGE TUMOR

Abstract

A 61-year-old woman was admitted to the hospital because of epigastric pain. Upper gastrointestinal series revealed a huge barium defect with irregular margin and barium spots in the center extending from the upper body to cardiac part of the stomach. Endoscopy of the upper G1 tract showed a huge elevated lesion with multiple ulcers in the upper body of stomach. Biopsy indicated no malignancy. Since the patient's general condition gradually deteriorated, a total gastrectomy with lymph nodes dissection (D2) was conducted with a suspicion of malignant submucosal tumor of the stomach. The resected material revealed an 11×10×5cm tumor with ulcer at the cardiac part of the stomach, and multiple ulcers other than that in the tumor. Histopathologically, the tumor was a remarkable thickening due to fibrosis extending from submucosal layer to serosa, to where eosinophilic leukocytes diffusely infiltrated. No nest of histionic cytes was demonstrated and no granuloma was formed.
It is very rare that eosinophilic gastritis formed a huge tumor. We report this rare case of eosinophilic gastritis which presented difficulty in differentiation from malignant tumors.