THE USEFULNESS OF POSTOPERATIVE FLUID MANAGEMENT BASED ON REDOX THEORY

Abstract

The usefulness of postoperative fluid management based on redox theory was investigated. Subjects were 36 patients who underwent high invasive surgeries or the operations with liver damage and whose arterial ketone body ratio (AKBR) had decreased less than 0.7 within 2 weeks after the operation. Of these 36patients, 21 patients were indicated the fluid management based on redox theory (group A) and the remaining 15 patients were not indicated (group B), and the two groups were compared for the postoperative clinical course. No significant differences were found in the perioprative background factors such as the age, gender, type of operation, ICG test, and the amount of intraoperative bleeding between group A and B. AKBRs recovered to more than 0.7 in 13 of 21 cases (62%) within additional 2 weeks (good course) in group A and in 5 of 15 in group B. No significant difference was seen in total cases, however, in the cases which had more than 2 organ damages postoperatively, group A had more cases (4/6, 67%) with good courses than those (1/10, 10%) in group B statistically. In conclusion, the measurement of AKBR enables the postoperative metabolic status to be assessed more accurately and the fluid management based on redox theory is considered to be necessary for the cases complicated with more than 2 organ damages postoperatively.