Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
GOBLET CELL CARCINOID OF THE APPENDIX WITH OVARIAN TUMOR OF BORDERLINE MALIGNANCY-A CASE REPORT-
Hirotoshi MARUOShigeo KAWAIShuji TOMINAGAShinichiro KUMEKoichi KANAIKuniko IIHARA
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1999 Volume 60 Issue 12 Pages 3206-3209

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Abstract
A 67-year-old woman was diagnosed as having acute appendicitis and underwent an appendectomy. The appendix was significantly red in color and swelled which were compatible with acute phlegmonous appendicitis macroscopically. Postoperative histology demonstrated that goblet-cell-like tumor cells extensively infiltrated to the submucosa with perineural invasion. These cells were mucin-producing and were diffusively shown as argyrophilic. Since the same treatment as in advanced cancer was considered appropriate, a right hemicolectomy with lymph node dissection and bilateral oophorectomy were added. No metastasis or residue was observed, but a minor ovarian papillary cystic tumor of borderline malignancy was noted. Goblet cell carcinoid of the appendix is known to be almost as malignant as cancer. Metastasis to the ovary is often found in patients with goblet cell carcinoid of the appendix, but concomitant primary ovarian tumor seems rare like in this patient.
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