Sweet disease is an inflammatory dermatologic disorder of unknown origin and is characterized by: 1) fever: 2) increase in neutrophile in peripheral blood; 3) painful elevated eruptions commonly occurred in the face, neck and extremities: and infiltration of neutrophile into the dermis. It is known that the disease can be associated with a variety of malignant tumors in a high frequency. Recently we experienced a case of Sweet disease with a cystadenoma of the pancreas.
A 43-year-old woman who had been diagnosed as Sweet disease 5 years before and had gained a remission by administration of steroids developed fever and dermal symptoms in October, 1994, and was diagnosed as having a recurrence of Sweet disease. Abdominal CT revealed a cystic lesion in the body and tail of pancreas. A resection of the body and tail of pancreas was performed. Operative findings included multilocular cyst 9 cm in diameter and a collection of 120ml of mucous in the body and tail of pancreas. Histopathologically mucinous cystadenoma of the pancreas was considered. It is thought that, in making the definite diagnosis of Sweet disease, the exploration of possible tumorous lesions should not be lacked.
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)