A CASE OF PRIMARY LIPOSARCOMA OF THE BREAST

Abstract

A case of primary liposarcoma of the breast is reported with a review of the relevant literature. A 60-year-old woman was seen at the hospital because of an inspection of her breasts. An elastic soft lump (15×10mm) was detected in the right breast (A). The lump revealed irregular in shape and heterogeneous in content by ultrasonography. However, no sign of abnormality was revealed on mammography and aspiration cytology and finally excisional biopsy led to a diagnosis of liposarcoma. Additional wide resection was done because of the positive surgical margin at the first extirpation and another focus of sarcoma was detected with positive margin even at the second resection. So a mastectomy was performed. Histologigal examination showed proliferation of lipoblast with hyperchromatic nuclei. The tumor was diagnosed as well-differentiated liposarcoma. No distant metastasis was noted. No postoperative additional therapy was done. The patient has been doing well without recurrence as of 5 years and 8 months after the last operation. Seventeen cases of liposarcoma of the breast have been reported in the Japanese literature, so far.