Abstract
A 53-year-old woman, who was under treatment at the department of medicine in our hospital for occasional abdominal pain, was referred to the department because of severe abdominal pain on August 31, 1997. The patient had been treated with prednisolone for systemic lupus erythematosus (SLE) since 1986 and had been on hemodialysis on twice a week basis for chronic renal failure since 1995. The abdominal pain was intensified and an emergency operation was performed. During operation, there were necrosis covering from the terminal ileum and descending colon to sigmoid colon, and perforation at the terminal ileum. The necrotic lesions were resected and a colostomy was performed. Hematoxylin-eosin study revealed ischemic necrosis of the intestinal and colonic wall, and thrombi were found in the mesenteric arteries. It is etiologically thought that angitis and antiphospholipid antibody positive might participate in the onset of the disease.
