A CASE LOCAL RECRRENCE OF THE RECTAL GASTROINTESTINAL STROMAL TUMOR (GIST) RESECTED BY TOTAL PELVIC EXENTERATION

Abstract

A 51-year-old man was admitted to the hospital because of perineal pain. There was previous history of undergoing abdominoperineal resection of the rectum for leiomyosarcoma of the rectum 6 years before admission. CT scan revealed local recurrence. Magnetic resonance imaging showed this tumor invading the prostate. So a total pelvic exenteration was performed. This tumor adhered to the prostate strongly, but did not invaded it. Pathological diagnosis was the rectal gastrointestinal stromal tumor (GIST) of uncommited type. Post operative couurse was uneventful and no evidence of recurrence has been found for 7 months.
We experienced three cases of local recurrence of the rectal GIST. More than 5 years had passed when recurrence occurred in two cases of them. These two patients are still alive now and pathological diagnosis was uncommitted type of the GIST in them. With further experience with many cases of GIST, we may be able to elucidate the correlations of immunophenotype with degree of malignancy, mode of recurrence and prognosis