A CASE OF CARBOHYDRATE ANTIGEN 19-9 PRODUCTING GASTRIC MUTINOUS ADENOCARCINOMA WITH TOO MUCH MUCOUS SECRETING

Abstract

We report a rare case of carbohydrate antigen (CA) 19-9 producting mucinous gastric cancer with too much secreting. A 46-year-old man was pointed out high value of serum CA19-9 by a routine health examination. So He was admitted to the hospital in order to rule out malignant disease. He was diagnosed as having advanced gastric cancer at the posterior wall on the antrum by gastrointestinal endoscopy.
Distal gastrectomy with regional lymph node dissection was performed. Microscopic examination revealed that the cancer was arose from mucous nodose and immunohistochemical stain of the resected material was positive for anti-CA19-9 monoclonal antibody was positive. The value of serum CA19-9 increased after admission and remarkaably decreased to the normal range after the gastrectomy. The normalized CA19-9 level has been kept up to nou for 3 years. Patients group with high CA19-9 valeu has a poor prognosis, and hence further strict observation of his clinical course will be nesessary.