Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
A CASE OF FAMILIAL ADENOMATOUS POLYPOSIS ASSOCIATED WITH MULTIPLE COLON CANCERS, EARLY GASTRIC CANCER AND CANCER OF THE MAJOR PAPILLA
Norio AKIYAMAMasatoshi ISHIZAKIShigefumi TANAKAKoichiro FUJITA
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2000 Volume 61 Issue 6 Pages 1613-1617

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Abstract
This paper presents a case of familial adenomatous polyposis (FAP) with primary cancers on multiple organs and hepatic metastases.
A 62-year-old woman was admitted to the hospital because of jaundice and epigastralgia. There were previous histories of undergoing a total colectomy for FAP with multiple colonic cancers 4 years before admission, undergoing an endoscopic resection for early gastric cancer 10 months, and having a dilatation of the intrahepatic bile duct 2 years after the colectomy.
A CT scan and a needle biopsy of the liver tumors revealed multiple liver metastases. An endoscopic examination by using a duodenoscope revealed the cancer around the orifice under the swollen papilla.
It was inferred that the papillary cancer may have already occurred 2 years before when the biliary dilatation was found, but was failed to be diagnosed correctly.
Since FAP is a systemic disease, an intensive screening is necessary for other extra-colonic organs.
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