MUCINOUS CYSTADENOMA OF THE PANCREAS WITH HIGH LEVELS OF TUMOR MARKERS (CEA, CA 19-9, AND CA 125) IN THE CYSTIC FLUID-REPORT OF A CASE-

Abstract

A 13-year-old girl was seen at the hospital because of a tumor of the left upper quadrant of abdomen. Tumor markers including CEA, CA19-9, and CA125 were all in normal ranges on general blood tests and biochemical studies. Imaging procedures revealed a 11×10cm cystic lesion with sep-tum at the pancreatic tail. A resection of the pancreatic body and tail was performed. No histologic malignancy was demonstrated and so mucinous cystadenoma was definitely diagnosed. CEA, CA19-9, and CA125 levels in the cystic fluid were as high as 1, 300ng/ml, 15, 817U/ml, and 134U/ml, respectively. CEA, CA19-9 and CA125 stainings by means of enzyme-anti-body method yielded positive responses in the epithelial cells of the cystic wall, indicating secretion of CEA, CA19-9, and CA125 to the cystic lumen. This case was thought to be an interesting instance in consideration of the significance of increases in these tumor markers in the cystic fluid. In addition, it is rare that mucinous cystadenoma is confirmed in such a juvenile like this case. The patient is the youngest among those patients in Japan as far as we could review.