Abstract
The primary malignant lymphomas of the large intestine account for about 10% of all malignant lymphomas of the gastrointestinal tract, and especially the perforated case is rare. This paper presents a case of perforated malignant lymphoma of the cecum. A 69-year-old man presented with lower abdominal pain. Abdominal X-ray films showed no free gas, but a gastrografin enema study showed whole circumferential stenosis at the cecum and extra-intestinal leakage of the contrast medium. Colonofiberscopy revealed a type 3 tumor at the cecum. Tissue biopsy revealed malignant lymphoma. We performed a right hemicolectomy with the diagnosis of perforated malignant lymphoma of the cecum.
The tumor was about 15cm in diameter. It was comparatively soft and type 3-like tumor with a large ulcer in the center. Histopathological examination revealed large, diffuse, B cell type malignant lymphoma. Post operative chemotherapy was not performed. During 99 days of follow-up observation after the operation, IL-2 receptor was useful as an indicator of recurrence.