TWO CASES OF DIABETIC MASTOPATHY

Abstract

Diabetic mastopathy is a specific type mastopathy characterized by prominent fibrosis of the mammary gland and perivascular or periductal infiltration of lymphcytes. So far 19 cases have been reported in this country. In this paper, we report two patients with diabetic mastopathy. Case 1: A 65-year-old woman with NIDDM who had been treated with insulin was pointed out a tumor in the D-region of the left breast by a medical checkup. Ultrasonic examination showed an 18×10mm low echoic mass. Mammography showed a polygonal mass with isodensity as breast glandular issue. Case 2: A 37-year-old woman with IDDM who had been treated with insulin for 26 years noticed a tumor in the C-region of the left breast. Ultrasonic examination showed a 10×8mm low echoic mass. No mass was visualized on mammography. In the two cases, these tumors were suggestive of cancer on palpation and ultrasonic examination and excisional biopsies were performed. Intraoperative pathologic findings showed keloidal fibrosis and periductal and perilobular infiltration of lymphocytes. Diabetic mastopathy was diagnosed.
Although the differentiation between this disease and breast cancer is difficult and requrires biopsy, it is a future subject whether needle biopsy or excisional biopsy is recommended.